Immune Checkpoint Inhibitors Market to Witness Steady Expansion, Estimated at USD 189.3 Billion by 2032: Allied

Immune Checkpoint Inhibitors Market Research Report 2024 – 2032

According to the report, the global immune checkpoint inhibitors market was valued at $40.1 billion in 2022, and is projected to reach $189.3 billion by 2032, registering a CAGR of 16.8% from 2023 to 2032.

Growing healthcare infrastructure, rise in prevalence of cancer conditions that require effective treatment and growing awareness regarding the use of immune checkpoint inhibitors are the factors that drive the growth of the global immune checkpoint inhibitors market. However, high cost of the inhibitors hinder market growth. On the contrary, a rise in healthcare expansion is expected to offer remunerative opportunities for the immune checkpoint inhibitors market during the forecast period.

The rise in cancer cases and the growing demand for effective treatment are anticipated to potentially drive the market growth. In addition, the growing initiatives in research and development of novel treatments and the rise in approvals from regulatory authorities are further driving the immune checkpoint inhibitors market growth.

Onkar Sumant – Manager
Life Sciences at Allied Market Research

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Immune Checkpoint Inhibitors Statistics:

  • The PD-1 inhibitor segment is expected to witness highest CAGR during the forecast period.
  • the lung cancer segment is expected to witness highest CAGR during the forecast period.
  • North America generated the largest revenue in 2022. However, Asia-Pacific is anticipated to grow at the highest CAGR during the forecast period.

Recession Scenario:

  • During a recession, the impact on the healthcare industry, including immune checkpoint inhibitors, can be significant.
  • The economic downturns may hinder technology investment. However, the growing number of cancer cases and the rising focus on effective management can drive interest in immune checkpoint inhibitors.
Factors affecting the growth of the Immune Checkpoint Inhibitors Market:

The growth of the Immune Checkpoint Inhibitors (ICI) market can be influenced by several factors:

  • Increasing Incidence of Cancer: The rising prevalence of cancer worldwide is a significant driver for the growth of the ICI market. As ICIs have shown promising results in treating various types of cancers, including lung cancer, melanoma, and others, their demand increases with the increasing incidence of these diseases.
  • Advancements in Cancer Immunotherapy: Ongoing advancements in cancer immunotherapy, including ICIs, drive market growth. Researchers are continuously discovering new targets for immune modulation, leading to the development of novel ICIs and combination therapies.
  • FDA Approvals and Regulatory Support: Regulatory approvals from agencies like the FDA (Food and Drug Administration) for new indications and drugs boost market growth by increasing accessibility and acceptance of ICIs in clinical practice.
  • Investments in Research and Development: Significant investments in R&D by pharmaceutical companies and academic institutions propel the development of new immune checkpoint inhibitors, improving treatment efficacy and patient outcomes.
  • Increasing Adoption of Combination Therapies: Combination therapies involving ICIs with other treatment modalities such as chemotherapy, targeted therapy, and radiation therapy are becoming more common. This trend drives market growth as it enhances treatment efficacy and expands the potential patient population.

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Regional Analysis:

North America held the highest market share in terms of revenue in 2022, accounting for more than three-fifths of the global immune checkpoint inhibitors market revenue the region’s robust healthcare infrastructure and advanced research capabilities, which facilitate early adoption and extensive utilization of innovative therapies, including immune checkpoint inhibitors. In addition, well-established clinical trials and research initiatives focusing on immune checkpoint inhibitors in various cancers, coupled with favorable regulatory policies is anticipated to fuel the market growth. However, the Asia-Pacific segment is projected to register highest CAGR of 18.8% during the forecast period owing to prevailing cancer cases and growing development in healthcare infrastructure with rise in adoption and demand for immune checkpoint inhibitors, thereby driving the growth of the market during the forecast period.

Market Segmentation:

The Immune Checkpoint Inhibitors (ICI) market can be segmented based on various factors including:

Type of Inhibitor: ICIs can be classified based on the type of checkpoint they target. Common types include:

  • PD-1 (Programmed Cell Death Protein 1) Inhibitors: Examples include pembrolizumab and nivolumab.
  • PD-L1 (Programmed Death-Ligand 1) Inhibitors: Examples include atezolizumab and durvalumab.
  • CTLA-4 (Cytotoxic T-Lymphocyte-Associated Protein 4) Inhibitors: Examples include ipilimumab.

Indication: ICIs are used to treat various types of cancers. Market segments can be based on the indication, including:

  • Melanoma
  • Non-small cell lung cancer (NSCLC)
  • Renal cell carcinoma (RCC)
  • Hodgkin’s lymphoma
  • Bladder cancer
  • Head and neck cancer
  • Others

Combination Therapy vs. Monotherapy: ICIs can be administered as monotherapy or in combination with other treatments such as chemotherapy, targeted therapy, or other immunotherapies. Market segments can be based on the treatment approach.

Region: The market can be segmented based on geographic regions such as North America, Europe, Asia-Pacific, and Rest of the World.

End User: Segmentation based on end users can include:

  • Hospitals
  • Cancer research centers
  • Clinics
  • Ambulatory surgical centers

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Leading Market Players: 

  • Merck And Co., Inc.
  • Astrazeneca Plc
  • F. Hoffmann-La Roche Ltd.
  • Merck KGaA
  • Regeneron Pharmaceuticals, Inc.
  • Bristol-Myers Squibb Company
  • Beigene, Ltd.
  • Shanghai Junshi Biosciences Co., Ltd.
  • Glaxosmithkline Plc

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